Humanized antibody, Keytruda/Pembrolizumab

Humanized antibodies are antibodies from non-human species whose protein sequences have been modified to increase their similarity to antibody variants produced naturally in humans.

Humanized antibody - Wikipedia
https://en.wikipedia.org/wiki/Humanized_antibody

Pembrolizumab

Drug

Pembrolizumab is a humanized antibody used in cancer immunotherapy. It blocks a protective mechanism on cancer cells, and allows the immune system to destroy those cancer cells. It targets the programmed cell death 1 receptor.Wikipedia

Formula: C₆₅₃₄H₁₀₀₀₄N₁₇₁₆O₂₀₃₆S₄₆

Molar mass: 146 kDa

Target: PD-1

ATC code: L01XC18 (WHO)

Source: Humanized (from mouse)

Trade name: Keytruda

雖然治療成功率並非百分百，但由於藥物對末期癌症患者亦適用，對於這些患者來說無疑是一個好消息。

不再根據腫瘤位置治療！全球首款基因向治療癌症藥物已獲 FDA 批准使用

眾所周知癌症是其中一種最難治癒的疾病，而且治療過程往往痛苦又漫長。過往癌症治療通常會根據腫瘤出現的位置去施藥，不過最近美國 Merck…

TECHNEWS.TW|作者：TECHNEWS 科技新報